Pathology MCQs
Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.
Q: Presence of Reed-Sternberg cells indicates
A) Non-Hodgkin lymphoma
B) Multiple myeloma
C) Chronic lymphocytic leukemia
D) Hodgkin lymphoma
✅ Correct Answer: D
Explanation: Reed-Sternberg cells are characteristic of Hodgkin lymphoma, aiding its diagnosis.
Q: Role of macrophages in granulomas
A) Histamine release
B) Vasodilation
C) Antibody production
D) Giant cell formation
✅ Correct Answer: D
Explanation: Macrophages transform into multinucleated giant cells within granulomas to contain persistent pathogens.
Q: Amyloidosis involves deposition of
A) Abnormal proteins
B) Calcium
C) Lipids
D) Glycogen
✅ Correct Answer: A
Explanation: Amyloidosis is caused by extracellular deposition of misfolded proteins that form insoluble fibrils.
Q: Anemia associated with chronic disease shows
A) Target cells
B) Microcytic hypochromic RBCs
C) Megaloblastic features
D) Normocytic normochromic RBCs
✅ Correct Answer: D
Explanation: Chronic disease often causes normocytic normochromic anemia due to impaired iron utilization.
Q: Hemosiderin is a storage form of
A) Calcium
B) Copper
C) Iron
D) Zinc
✅ Correct Answer: C
Explanation: Hemosiderin stores excess iron in tissues, visible with Prussian blue staining.