Pathology MCQs

Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.

Q: The main function of mast cells in inflammation
A) Secrete antibodies
B) Synthesize collagen
C) Release histamine
D) Phagocytosis
โœ… Correct Answer: C
Explanation: Mast cells release histamine and other mediators that initiate vascular changes in inflammation.
Q: Atypia in cells is most often associated with
A) Pre-malignant or malignant transformation
B) Benign conditions
C) Normal development
D) Nutritional deficiency
โœ… Correct Answer: A
Explanation: Cellular atypia refers to abnormal morphology that may indicate dysplasia or neoplasia.
Q: Increased ESR (erythrocyte sedimentation rate) suggests
A) Increased red cell count
B) Normal immune activity
C) Acute blood loss
D) Ongoing inflammation
โœ… Correct Answer: D
Explanation: ESR rises in response to acute phase reactants during inflammation.
Q: A common feature of malignant neoplasms
A) Encapsulation
B) Uniform nuclei
C) Slow growth
D) Metastasis
โœ… Correct Answer: D
Explanation: Metastasis is a defining feature of malignant tumors, indicating their ability to spread.
Q: Anemia in chronic disease is typically
A) Normocytic and normochromic
B) Macrocytic and megaloblastic
C) Microcytic and hypochromic
D) Hemolytic and regenerative
โœ… Correct Answer: A
Explanation: Anemia of chronic disease usually presents as normocytic normochromic due to impaired iron utilization.