Pathology MCQs
Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.
Q: Epithelioid cells in granulomas derive from
A) Neutrophils
B) Macrophages
C) B cells
D) Mast cells
✅ Correct Answer: B
Explanation: Macrophages transform into epithelioid cells during granulomatous inflammation.
Q: Hyperplasia can be physiological in
A) Endometrial lining during menstrual cycle
B) Scar formation
C) Atherosclerosis
D) Prostate cancer
✅ Correct Answer: A
Explanation: Endometrial hyperplasia during the menstrual cycle is a normal, hormone-regulated process.
Q: Loss of nucleus in cell injury is referred to as
A) Pyknosis
B) Karyorrhexis
C) Karyolysis
D) Lysis
✅ Correct Answer: C
Explanation: Karyolysis is the dissolution of nuclear material due to enzymatic degradation.
Q: Fat necrosis is commonly seen in
A) Myocardial infarction
B) Brain infarct
C) Liver cirrhosis
D) Breast trauma
✅ Correct Answer: D
Explanation: Fat necrosis often results from trauma to fatty tissues like the breast or pancreas.
Q: Primary mediator of fever during inflammation
A) TNF-beta
B) IL-4
C) IL-10
D) IL-1
✅ Correct Answer: D
Explanation: Interleukin-1 acts on the hypothalamus to raise body temperature and induce fever.