Pathology MCQs
Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.
Q: Proliferation of fibroblasts and deposition of collagen results in
A) Fibrosis
B) Angiogenesis
C) Granulation tissue
D) Inflammation
✅ Correct Answer: A
Explanation: Fibrosis involves excessive collagen deposition by fibroblasts after tissue injury.
Q: Cause of caseous necrosis in tuberculosis
A) Ischemia
B) Coagulative necrosis
C) Chemical injury
D) Immune response to mycobacteria
✅ Correct Answer: D
Explanation: The immune system’s response to Mycobacterium tuberculosis leads to caseous necrosis.
Q: Karyolysis indicates
A) Chromatin condensation
B) Cell proliferation
C) Nuclear fragmentation
D) Fading of nuclear basophilia
✅ Correct Answer: D
Explanation: Karyolysis refers to the loss of staining in the nucleus due to DNA degradation.
Q: A hallmark of reversible cell injury
A) Nuclear fragmentation
B) Membrane rupture
C) Mitochondrial swelling
D) Loss of lysosomes
✅ Correct Answer: C
Explanation: Mitochondrial swelling is a characteristic of reversible cell injury caused by ATP depletion.
Q: Chronic inflammation is characterized by
A) Neutrophil predominance
B) Fibrosis and tissue destruction
C) Lack of immune response
D) Short duration
✅ Correct Answer: B
Explanation: Chronic inflammation involves persistent immune response and ongoing tissue damage.