Pathology MCQs
Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.
Q: Fibrinoid necrosis is characteristically seen in
A) Myocardial infarction
B) Malignant hypertension
C) Rheumatic fever
D) Fat embolism
✅ Correct Answer: B
Explanation: Fibrinoid necrosis occurs in vessel walls during immune-mediated or severe hypertensive damage.
Q: A key feature of liquefactive necrosis
A) Fibrous encapsulation
B) Calcium deposition
C) Tissue hardening
D) Tissue liquefaction due to enzymatic digestion
✅ Correct Answer: D
Explanation: Liquefactive necrosis results in enzymatic digestion of dead cells, forming a liquid mass.
Q: The earliest change in reversible cell injury
A) Cellular swelling
B) Loss of nucleus
C) Nuclear fragmentation
D) Cell membrane rupture
✅ Correct Answer: A
Explanation: Cellular swelling occurs first due to failure of ATP-dependent ion pumps.
Q: Pseudomembranous inflammation is classically seen in
A) Clostridium difficile colitis
B) Asthma
C) Pneumonia
D) Hepatitis A
✅ Correct Answer: A
Explanation: Clostridium difficile infection causes necrosis and formation of a pseudomembrane over colonic mucosa.
Q: Hyperplasia is defined as
A) Increase in cell number
B) Increase in cell size
C) Uncontrolled growth
D) Abnormal cell development
✅ Correct Answer: A
Explanation: Hyperplasia results from hormonal or compensatory stimuli and increases the number of normal cells.