Pharmacology MCQs
Pharmacology MCQs help learners understand the actions, interactions, uses, and side effects of various drugs. These questions cover pharmacokinetics, pharmacodynamics, drug classifications, and toxicology. Practicing them aids in mastering this crucial medical subject and performing well in exams such as MDCAT, USMLE, FCPS, and NTS.
Q: Drug used to manage alcohol withdrawal seizures
A) Fluoxetine
B) Haloperidol
C) Diazepam
D) Phenytoin
✅ Correct Answer: C
Explanation: Benzodiazepines like diazepam are first-line agents for managing alcohol withdrawal symptoms.
Q: Preferred agent for treating hypertension in pregnancy
A) Propranolol
B) Lisinopril
C) Methyldopa
D) Ramipril
✅ Correct Answer: C
Explanation: Methyldopa is considered safe during pregnancy and commonly used to manage hypertension.
Q: Mechanism by which proton pump inhibitors reduce acidity
A) Inhibiting gastric ATPase
B) Blocking cholinergic receptors
C) Neutralizing acid
D) Blocking H2 receptors
✅ Correct Answer: A
Explanation: PPIs inhibit the H⁺/K⁺ ATPase in gastric parietal cells, reducing acid secretion.
Q: Rifampin changes urine color to
A) Yellow
B) Orange-red
C) Green
D) Blue
✅ Correct Answer: B
Explanation: Rifampin causes orange-red discoloration of urine, sweat, and tears due to its pigment.
Q: Beta-2 agonists like salbutamol are used for
A) Bronchodilation
B) Diuresis
C) Analgesia
D) Sedation
✅ Correct Answer: A
Explanation: Beta-2 agonists relax bronchial smooth muscle, making them effective in asthma.
Q: Drug causing gingival hyperplasia
A) Metoprolol
B) Ciprofloxacin
C) Nifedipine
D) Omeprazole
✅ Correct Answer: C
Explanation: Calcium channel blockers like nifedipine can induce gingival overgrowth.
Q: Sulfonylureas stimulate insulin release from
A) Pancreatic beta cells
B) Liver
C) Muscle
D) Adipose tissue
✅ Correct Answer: A
Explanation: Sulfonylureas close potassium channels in beta cells, leading to insulin release.
Q: Drug of choice in malaria caused by P. vivax
A) Chloroquine
B) Quinine
C) Artemether
D) Doxycycline
✅ Correct Answer: A
Explanation: Chloroquine is effective against P. vivax in areas where resistance is not present.
Q: Mechanism of action of heparin
A) Inhibits platelet aggregation
B) Inhibits vitamin K
C) Blocks thrombin directly
D) Activates antithrombin III
✅ Correct Answer: D
Explanation: Heparin enhances the activity of antithrombin III, which inactivates clotting factors.
Q: Antibiotic class targeting bacterial ribosomes
A) Penicillins
B) Quinolones
C) Aminoglycosides
D) Cephalosporins
✅ Correct Answer: C
Explanation: Aminoglycosides bind to the 30S subunit of bacterial ribosomes, inhibiting protein synthesis.