Pathology MCQs
Pathology MCQs assess knowledge of disease mechanisms, histopathology, and systemic conditions. Covering organs like liver, lungs, heart, and kidneys, they help MDCAT, USMLE, NTS, and FCPS aspirants strengthen concepts and clinical understanding.
Q: Anaplasia is a feature of
A) Healing
B) Malignancy
C) Immunity
D) Differentiation
✅ Correct Answer: B
Explanation: Anaplasia involves the loss of cellular differentiation and is a hallmark of cancer.
Q: Giant cell formation is a typical feature of
A) Necrosis
B) Chronic inflammation
C) Coagulation
D) Acute trauma
✅ Correct Answer: B
Explanation: Chronic inflammatory responses often lead to the fusion of macrophages into multinucleated giant cells.
Q: Amyloidosis results from
A) Iron overload
B) Abnormal protein deposition
C) DNA mutation
D) Excess calcium
✅ Correct Answer: B
Explanation: Amyloidosis is characterized by extracellular deposits of misfolded protein aggregates.
Q: The earliest cellular response to hypoxia is
A) ATP depletion
B) Lipid accumulation
C) Fibrosis
D) DNA fragmentation
✅ Correct Answer: A
Explanation: Hypoxia reduces oxygen delivery, causing early ATP loss and impairing energy-dependent processes.
Q: Hypertrophy results in
A) Reduced organ mass
B) Cell number decrease
C) Increased cell size
D) Mitotic failure
✅ Correct Answer: C
Explanation: Hypertrophy is the enlargement of cells, often in response to increased workload.