Pharmacology MCQs

Pharmacology MCQs test knowledge of drug actions, interactions, classifications, pharmacokinetics, pharmacodynamics, and toxicology. Ideal for MDCAT, USMLE, FCPS, and NTS preparation, these quizzes strengthen medical understanding and boost exam performance through targeted practice.

Q: Therapeutic use of methotrexate
A) Parkinsonism
B) Rheumatoid arthritis
C) Hyperthyroidism
D) Diabetes mellitus
โœ… Correct Answer: B
Explanation: Methotrexate is used in low doses to suppress immune activity in autoimmune diseases.
Q: Cisplatin is most toxic to the
A) Bone marrow
B) Kidneys
C) Liver
D) Lungs
โœ… Correct Answer: B
Explanation: Nephrotoxicity is the dose-limiting adverse effect of cisplatin.
Q: Drug used to treat bradycardia
A) Digoxin
B) Labetalol
C) Propranolol
D) Atropine
โœ… Correct Answer: D
Explanation: Atropine blocks vagal stimulation, increasing heart rate.
Q: Mechanism of action of sulfonamides
A) Inhibit DNA gyrase
B) Bind ribosomal subunit
C) Inhibit cell wall synthesis
D) Block folic acid synthesis
โœ… Correct Answer: D
Explanation: Sulfonamides competitively inhibit dihydropteroate synthase, blocking folate production.
Q: Adverse effect of chronic corticosteroid therapy
A) Hyperkalemia
B) Bradycardia
C) Osteoporosis
D) Hypoglycemia
โœ… Correct Answer: C
Explanation: Long-term corticosteroid use leads to bone resorption and osteoporosis.